Simvastadin in depression: The title lost!-

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By increasing cholesterol levels, statins are often used - known so far.But can lipidsenker simvastatin and depression?Spoiler: He is complicated.

At first glance, there was a substance that had no evidence, they were unjustified: who knows the psyche and psyche and who knows the animal?The German Research Group has already looked great - in large, placebo-spontroll studies, with patients with obese and great depression.

The idea of ​​Simpastatin usage is not new.They's suggestion is not the best of the animal-ie nmda vicamer.The Totophysiology of the Darkness is associated with neuro -inflamarary needs that remaining of Northine and Neuroendocrine.

Therefore, some studies have checked the use of simvastatin to make further protection for protection protection.Meta-focuses are made of 2016 at the end of the specified tournament that is further adjustable.As simvastatin.However, all situations are heterogeneous materials, as some evaluations do not get all the impacts at all.

Positive effects are particularly prominent in light to moderate depression, especially in small studies.

The German Research Team has become a declaring service from Profrary Berlin.Unlike past, short or partial studies, this investigation made a huge housing, so the planned golden center controlling many double-blind centers.I specifically studied a patient group that is very clinical relating to severe and obese (BMI ≥ 30).The study collected a unified anti-manchent treatment (ascherapram 20 mg) with a fixed diet of Sympstatatatin (40 mg) or fake.The goal was to obey the purposes for the symptoms of depression in the circumstances of realistic treatment.160 patients participated.The endpoint was the endpoint.The degrees of motheros (Martagometery-Whemsberg) after the initial 12 weeks.The secondary endpoint includes the quality of a self-I-2, life, social work and biochemical parameters.

The bottom line: Symbistatin does not show significant additional use of the use of placebo about the symptoms of depression.The favorite group has the use of therapy promotional therapy that can be compared.Influencing the patient's psychological symptoms.

The learning clearly shows that Sinvastatite has no additional antidepressant benefits in patients with depression and obesity with the dosage and duration of examined therapy.Anterior positives of minor and methodologically limited studies could not be replicated.Well-dockened cardiovascular effects remain unfectly: they justify regulation in the feeling of cardiovascular prevention - spaceally in patients psychiatric ones that are usually under proof here.

The reason can be erupted in previous studies: patients are often intended by the insignificant symptoms - in the same excellence groups and the production prices - and the produceologist is transherent to clinical practice.

The decision to evaluate this patient's association is not unexpected.Obstacles, imbalances of HPA and neurorecin are possible.Breath life, social issue, unprotected characteristic and inability to make agricultural depression, increasing abroad.

There are therapeutic results for this closer knowledge: it emphasizes the need to identify interdisciplinary in the early stages and if necessary - but new research provides valuable impetus on future therapeutic approaches.

Simvastatin has many pharmacological properties, but it cannot be proven antidepressants in patients with respirators in current research.Simvastatin is an anti-inflammatory and beneficial for metabolic parameters, but the usual use of depression treatment cannot be justified.- For example, to ask whether patients can have additional treatment.Toopor, Simvastatins remains important to process risks, but not antidepressant.

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